Haldol (Haloperidol)

Haldol Review

Haldol is used to treat schizophrenia. It is also used to control motor and speech tics in people with Tourette's syndrome.

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Haldol Drug Class and Mechanism

Haldol is an antipsychotic medication. It works by changing the actions of chemicals in your brain.

Haldol Uses

A comprehensive review of haloperidol has found it to be an effective agent in treatment of symptoms associated with schizophrenia. Haloperidol is also used in the control of the symptoms of: Acute psychosis, such as drug psychosis (LSD, psilocybin, amphetamines), psychosis associated with high fever or metabolic disease Acute manic phases until the concomitantly given first-line drugs such as lithium or valproate are effective Hyperactivity, aggression. Acute delirium Otherwise uncontrollable severe behavioral disorders in children and adolescents Agitation and confusion associated with cerebral sclerosis Adjunctive treatment of alcohol and opioid withdrawal Treatment of neurological disorders such as tic disorders, Tourette syndrome, and chorea Treatment of severe nausea/emesis (postoperative, side-effects of radiation and cancer chemotherapy) Adjunctive treatment of severe chronic pain, always together with analgesics Therapeutic trial in personality disorders such as borderline personality disorders Also used in the treatment of Intractable hiccups Some weeks or even months of treatment may be needed before a remission of schizophrenia is evident. In some clinics the use of atypical neuroleptics (e.g. clozapine, risperidone, olanzapine, ziprasidone) is generally preferred over haloperidol, because these drugs have an appreciably lower incidence of extrapyramidal side-effects. Each of these drugs, however, has its own spectrum of potentially serious side-effects (e.g. agranulocytosis with clozapine, weight gain with increased risk of diabetes and of stroke). Atypical neuroleptics are also much more expensive and have recently been the subject of increasing controversy regarding their efficacy in comparison to older products and side effects.

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Haldol Side Effects

Propranolol is generally well tolerated, and side effects are mild and transient. Rare side effects include abdominal cramps, diarrhea, constipation, fatigue, insomnia, nausea, depression, dreaming, memory loss, fever, impotence, lightheadedness, slow heart rate, low blood pressure, numbness, tingling, cold extremities, sore throat, and shortness of breath or wheezing.

Haldol Pregnancy

Data from animal experiments indicate haloperidol is not teratogenic, but is embryotoxic in high doses. In humans, no controlled studies exist. Unconfirmed studies in pregnant women revealed possible damage to the fetus, although most of the women were exposed to multiple drugs during pregnancy. Following accepted general principles, haloperidol should only be given during pregnancy if the benefit to the mother clearly outweighs the potential fetal risk. Haloperidol, when given to lactating women, is found in significant amounts in their milk. Breastfed children sometimes show extrapyramidal symptoms. If the use of haloperidol during lactation seems indicated, the benefit for the mother should clearly outweigh the risk for the child. Consider termination of breastfeeding.

Haldol Overdose

Canadian residents should call their local poison control center directly. Symptoms of overdose may include unusually slow heartbeat, severe dizziness, slow or shallow breathing, weakness, or fainting.

Haldol More Information

Haldol is to be used only by the patient for whom it is prescribed. Do not share it with other people. If your symptoms do not improve or if they become worse, check with your doctor.